Use of tranexamic acid as a blood-saving method in patients of liposuction and other aesthetic surgeries: a retrospective study
Introduction: Liposuction is among the most grueling procedures in esthetic plastic surgery. Despite the existing evidence of tranexamic acid (ATX) as a blood-saving method in surgeries of different surgical specialties, its use in plastic-esthetic surgery is scarce, especially in liposuction.
Goal: To determine the impact of ATX on blood loss in patients who have undergone liposuction surgical procedures.
Methods: A total of 102 patients met the inclusion requirement criteria. All of them received balanced general anesthesia. 10–15 mg/kg IV of ATX (1 g on average) was administered 20 min before surgery, and so it continued for the first 24 h of postoperatory with 500 mg/IV every 8 h. Blood count samples were taken 12–20 h postoperatory.
Results: The hematocrit showed a median of 42.6% presurgical and 33.5% postsurgical. On the other hand, the presurgical hemoglobin median was 14.2 g/Dl (Interquartile ranges [RIC]) 13.4–15) and postsurgical of 11.4 (RIC: 10.6–12.1); giving a median difference of presurgical and postsurgical hemoglobin of −2.8 (RIC: −3.6 to −2.1), the difference percentage of hemoglobin concerning the base was −19.5% (RIC: –25.0 to −14.9).
Conclusion: The use of ATX in liposuction seems to grant the same benefits in terms of bleeding reduction, hemoglobin stabilization, hematocrit, and necessity of transfusions compared with operations of other surgical specialties. The dose used in this study is adequate and safe in order to achieve these goals and is consistent with the literature. More analytic studies in the field are necessary to reinforce these hypotheses.
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